Rated 3rd most miserable state.

Above, No.1 West Virginia and Kentucky, Mississippi ranks 3rd in this miserable list.

3. Mississippi

Well-being index score: 63.4
Life expectancy: 74.8 (the lowest)
Obesity: 34.0 percent (the highest)
Median household income: $36,851 (the lowest)
Adult population with high school diploma or higher: 81.0 percent (3rd lowest)

Mississippi is the poorest state in the nation by a number of metrics. Its median household income is $36,851, which is the lowest in the country. It also has the highest poverty rate in the country at 21.8 percent. Mississippi has among the lowest rates of adults with a high school diploma or more. Health is also a major issue in the state. Mississippi has the lowest life expectancy in the country, at 74.8 years -- almost four years less than the national average. Mississippi has the highest obesity rate in the nation at 34 percent. It also has among the five highest rates of diabetes, heart disease, cancer and tobacco use among states. It is no wonder that Mississippi residents feel so poorly as measured by the third-lowest well-being score.